Essential Biochemistry - Enzymes (Section 2 - No. 49)
Which of the following is a characteristic of irreversible inhibitors?
They bind reversibly to the enzyme.
They often form covalent bonds with the enzyme.
Their effect can be reversed by adding more substrate.
They do not affect the enzyme's structure.
Forklaring
Irreversible inhibitors often form covalent bonds with the enzyme, permanently inactivating it.